In Classical Mythology, Pandora was the wife from Prometheus’s brother called Epimetheus. Prometheus created the humans with his magical powers and with the objective to make the humans be more comfortable and unworried he hid all the illnesses and the bad things that could be not good for the humanity in a magical box. Some time later, Prometheus was punished by Zeus and he told his brother not to open the box. Unfortunately, Pandora opened the box and all the bad things came out of it and the world became the world that nowadays is.
In the Avatar movie, Pandora Is the moon where the Navis live. I suppose that this moon is called like that because in that place there are a lot of grey magical rocks that supply to the humans a lot of money and power. For that reason, we could say that these rocks would be one of the causes of the corruption and the fact to destroy that place full of nature. In conclusion, the corruption and the ambition are two of the bad things that were at Pandora’s box.